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KMID : 0370219930370060555
Yakhak Hoeji
1993 Volume.37 No. 6 p.555 ~ p.560
Total Synthesis of 11-Deoxy-beta-rhodomycinone Antitumor Antibiotics
³ë¿µ¼è/Rho YS
°­È¥¼ö/½ÅÈ«½Ä/Kang HS/Sin HS
Abstract
Methyl 3-[(phenylsulfonyl)methyl]-1,4,8-trimethoxy-2-naphthoate(7) preparad by 3 steps was condensed with 5-ethyl-2-cyclohexen-l-one(8) to afford the teracyclic aromatic ring system compound 10, which was stepwise converted into the precursor of 11-Deoxy-beta-rhodomycinone by means of various functional groups transformation.
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